Hyaluronic Acid in Skin Repair and Wrinkle Reduction
Hyaluronic Acid is a polymer that was first isolated from vitreous humor in the 1950s. It is high in uronic acid content and its name is derived from hyalos, the Greek work for vitreous, and uronic acid. Hyaluronic Acid (HA) is a major component of skin and is active in repair of damaged tissue and plays a significant role in tissue hydration and the growth of skin cells. For example, when skin is sunburned from excessive ultraviolet radiation, the cells in the skin produce less HA.
Hyaluronic Acid comprises a major part of the tissues near newly forming cells. As a result, it is an important component in rapid healing of wounds in fetal organisms where scars do not form. Actions initiated by HA at the cellular level are integral to the amazing process of fetal development.
Numerous tissues of the body, such as skin, cartilage, and the vitreous of the eye contain abundant amounts of HA. As a result, it works well for medical applications involving these tissues. The first HA biomedical product was developed in the 1970s and is approved for use in cataract surgery, corneal transplants, retinal detachment repair, and glaucoma surgery.
Hyaluronic Acid is produced in higher quantities during the cell proliferation phase of wound healing. In addition to providing structural support for the wound, application of topical HA is known to increase the rate of healing of wounds in the skin of animals. It plays a role in the inflammatory phase of wound healing by enhancing the production of cytokines and enhancing the function of new cell growth in wound healing. Low molecular weight Hyaluronic Acid has been used as a topical cream to protect newly formed tissue from scavenging free radicals.
Once people reach 50 years of age, their bodies have less than half the amount of HA they in their younger years. About 50% of the Hyaluronic Acid in our bodies is found in the upper layer of our skin and connective tissue. Inadequate levels of Hyaluronic Acid cause skin to appear wrinkled and saggy. Other common features of older skin include a breakdown of collagen structures, decreased collagen production, and high levels of enzymes that destroy collagen. This situation accelerates the process of aging in a never ending cycle.
Because age-related reductions in HA levels correlate with wrinkled skin, effective anti-aging attempts to rejuvenate skin and result in a youthful appearance by revitalizing damaged tissue should include this important substance.
Lee Slaney is a licensed esthetician. More information on products recommended in this article can be found at http://www.MangoMadnessSkinCare.com and http://www.mangomadnessskincare.com/Moisturizers-p-1-c-9.html.
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